UW-Madison researchers have developed a method of enriching microbial DNA in a plasma DNA sample for early detection of microbial infection. Previously, this group found that microbial DNA fragments a...
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UW-Madison researchers have developed a method for increasing butyrate production in the gut. The method includes delivering a microbial community that include certain bacteria, yeasts, and other micr...
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UW-Madison researchers have developed a method to optimize the production of reuterin in bacterial cells that contain the reuterin production pathway (i.e., the pdu operon). The inventors compared the...
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UW-Madison researchers have developed HeLa cell-adapted Rhinovirus-C (RV-C) variants that induce a strong cytopathic effect and replicate vigorously in HeLa-E8 cells. The inventors had previously show...
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Metagenomics is the study of genetic material from environmental samples for detecting microbes, especially pathogens. It is increasingly used within clinical and industrial settings. While metagenomi...
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UW-Madison researchers have developed a number of variants of lytic strain L. reuteri ∆Φ1attB1∆Φ2∆attB2 (WARF case P170020). They are: L. reuteri∆Φ1, in which prophage #1 is deleted from th...
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UW-Madison researchers have developed a CRISPR-based genome editing tool to study and modify PULs in B. uniformis. The B. uniformis PULs show distinct glycan-degrading functions and transcriptional co...
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UW-Madison researchers disclose two mutant Bacteroides strains, BU ΔPUL18 and BU ΔPUL37, each with characteristics that could be useful in modulating the gut microbiome.
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UW-Madison researchers have cloned, sequenced and characterized the genome from an isolate of the RV-C45 genotype, and they’ve provided the cDNA for a high titer HRV-C (C45-2A-D41K), as well as the ...
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Systems and methods for determining genetic variations of an organism for performing a physiological function. The systems include a number of modules that can be integrated into existing metabolic en...
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Provided are systems and methods for accurately determining flux distribution in organisms or cells without use of metabolic flux analysis data. The methods include estimating flux distributions in mu...
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Plant biomass represents a vast and renewable source of energy. However, harnessing this energy requires breaking down tough lignin and cellulose cell walls. In nature, certain microbes can deconstruc...
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Interspecies yeast hybrids are critical for producing commercially important fermentation products such as Belgian ale, certain ciders and cold-fermented wines. As one major example, lager beer, the m...
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The therapeutic and biochemical properties of proteins including antibodies can be enhanced by custom chemical functionalization that enables modifications, such as small molecule drug conjugation, PE...
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Approximately 20 percent of human proteins – including many of high pharmaceutical relevance – are believed to contain disulfide bonds critical for proper structure and function. However, producin...
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Fatty acids generally can be classified as straight-chain or non-straight-chain. Non-straight-chain fatty acids are less abundant and highly valued in dietary supplements, cosmetics, pharmaceuticals, ...
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Pyruvate is a starting material for synthesizing a variety of biofuels and chemicals. It can be readily converted into more than 60 commercial chemicals, including ethanol and several active pharmaceu...
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Fungi produce a variety of chemical compounds called secondary metabolites that possess useful pharmaceutical properties. These compounds are invaluable platforms for developing front-line drugs. They...
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Ethanol obtained from the fermentation of grains and sugars is being blended with gasoline to bolster dwindling petroleum supplies. The alcohol increases combustion efficiency and octane value, and ca...
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Acyl carrier protein (ACP) is a small lipid carrier protein involved in fatty acid biosynthesis and in the solubilization of fats to make them metabolically available. The molecule is difficult to obt...
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Microorganisms adapted to grow in exceptionally harsh environments, such as hot springs and arctic soils, are a potentially vast source of novel metabolic processes, antibiotics, enzymes and other pro...
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Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be brought into culture by standard techniques represent only ...
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Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be cultured using standard techniques represent only a small f...
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Microorganisms adapted to grow in exceptionally harsh environments, such as hot springs and arctic soils, are a potentially vast source of novel metabolic processes, antibiotics, enzymes and other pro...
Learn More

Microorganisms adapted to grow in exceptionally harsh environments, such as hot springs and arctic soils, are a potentially vast source of novel metabolic processes, antibiotics, enzymes and other pro...
Learn More