Improved MRI methods are needed to diagnose nonalcoholic fatty liver disease (NAFLD), the most common cause of liver disease in the Western world. Promising studies have demonstrated the utility of Tl...
Learn More

Magnetic resonance spectroscopy (MRS) is a technique that measures a subject’s nuclear magnetic resonance (NMR) to produce spectra of its tissue components.  In medical diagnosis and treatment, it ...
Learn More

A system and method are provided for controlling a magnetic resonance imaging system to perform a gradient echo pulse sequence that includes varying a phase of an RF pulse of the gradient echo pulse s...
Learn More

In magnetic resonance imaging (MRI), tissue is scanned using magnetic fields that excite atoms and cause them to emit signals. These nuclear magnetic resonance (NMR) signals can be processed into an i...
Learn More

Magnetic resonance (MR) imaging technology is used to measure nuclear magnetic resonance (NMR) from various substances in human tissue to produce medical images for qualitative and quantitative assess...
Learn More

Quantifying the amount of fat in the liver is crucial for the detection of non-alcoholic fatty liver diseases including steatosis, fibrosis, cirrhosis and liver failure.  Accurate fat measurements ca...
Learn More

Magnetic resonance imaging (MRI) is used to measure nuclear magnetic resonance (NMR) from various substances in human tissue to produce medical images for qualitative and quantitative assessments.  T...
Learn More

Chemical shift-based multi-echo water-fat separation methods are used increasingly in MRI clinical applications to distinguish between water and fat nuclear magnetic resonance (NMR) signals. Water and...
Learn More

Nuclear magnetic resonance is the property of magnetic nuclei used in medical imaging techniques like MRI to produce images. The nuclear magnetic resonance of water is known to be dependent on tempera...
Learn More

Iron is an essential nutrient for the human body but is toxic in excess. Iron overload is a particular hazard to patients requiring regular blood transfusions. Treatment for patients with iron overloa...
Learn More

In magnetic resonance imaging (MRI), the amount of data required to reconstruct an image can be decreased using ‘partial k-space’ sampling. This type of sampling enables shorter breath-holds, redu...
Learn More

Magnetic resonance imaging (MRI) of metallic implants can be challenging because metal and surrounding tissue impact the main magnetic field differently. Such magnetic field inhomogeneities cause off-...
Learn More

Visualizing a body’s internal structures by MRI is an essential clinical practice. Yet acquiring images in the presence of metal, like the steel screws of an implant, remains challenging because of ...
Learn More

Magnetic resonance parametric mapping is a general framework for measuring important biomarkers. In the process, several images from the same field of view are obtained using different acquisition par...
Learn More

Chemical shift-based multi-echo water-fat separation methods have seen increased use in routine magnetic resonance imaging (MRI) clinical applications. These methods involve collecting multiple echoes...
Learn More

An excess of visceral adipose tissue (VAT), or fat stored in the abdomen, is known to be a dominant risk factor in developing metabolic syndrome, the not fully understood clustering of metabolic and c...
Learn More

Mapping of effective transverse relaxation rate (R2*) relaxivity has important applications in magnetic resonance imaging (MRI) including blood oxygenation level dependent functional imaging, detectio...
Learn More

UW–Madison researchers have previously developed “IDEAL,” a multi-echo chemical species separation technique that uses iterative decomposition of water and fat with echo asymmetry and least squa...
Learn More

NMR signal contributions from water and fat are separated using a model of the fat resonant frequency spectrum that has multiple resonant peaks. The relative frequencies of the multiple fat spectrum p...
Learn More

UW-Madison researchers have developed a novel clinical MRI method for quantitative T2 mapping. The new T2 mapping method uses RF-phase modulated dual echo steady-state sequence (DESS). T2 information ...
Learn More

UW-Madison researchers have developed an automated process to accurately quantitate breast density using MR images.  The methods assess tissue properties within a region of interest (ROI) using chem...
Learn More

Proton density fat fraction (PDFF) and R2* estimated using quantitative chemical shift-encoded MRI (CSE-MRI) are well-established quantitative biomarkers of liver fat content. As such, CSE-MRI methods...
Learn More

UW Researchers have developed a novel MRI diffusion mapping method using phase-based diffusion mapping (PBD.) The technique provides a novel way to measure the apparent diffusion coefficient (ADC) of ...
Learn More

A method for producing images of a subject containing M spin species using a magnetic resonance imaging (MRI) system includes obtaining N k-space data matrices from N k-space data sets acquired with t...
Learn More

The ability to quantify fat concentration in the body has become increasingly important given the rise in obesity and related comorbidities. Likewise, the ability to quantify iron concentration is imp...
Learn More