Wildfires occur naturally in many ecosystems worldwide; however, the frequency of wildfires has increased in recent years. The United States National Interagency Fire Center reports that the total bur...
Learn More

UW-Madison researchers have developed a nonionic cleavable surfactant (NCS) for mass spectrometry (MS)-based proteomics and analysis. Specifically, NCS was designed and synthesized to include a cleava...
Learn More

A UW-Madison researcher has developed a celestial guidance system that uses radio imaging of celestial bodies including the galactic plane received by an interferometric antenna array to provide robus...
Learn More

UW-Madison researchers have developed a set of novel isobaric chemical tags, DiLeu-Biotin-Azide (DBA), that could be useful in proteomics, particularly quantification of post translational modificatio...
Learn More

Soil produces or consumes gases such as carbon dioxide, methane, nitrous oxide, ammonia, and oxygen through normal biological and geological processes. Current soil gas-flux measurement systems are ex...
Learn More

UW-Madison researchers developed a new process for preparing proteins, lipids, and metabolites for MS-based multi-omics. The process is based on an monophasic extraction solvent (e.g., n-butanol) that...
Learn More

A UW researcher has developed a digital system for controlling pressure oscillations within a wellbore, as well as associated monitoring equipment and analysis codes. The equipment includes a wellhead...
Learn More

Fluorescent microscopes, including wide-field, confocal and super-resolution, are widely used instruments in a variety of research fields but require routine calibration and maintenance. Calibration r...
Learn More

Single particle cryo-electron microscopy (cryo-EM) is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many n...
Learn More

Single particle cryo-electron microscopy is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many new biologi...
Learn More

Single particle cryo-electron microscopy (cryo-EM) is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many n...
Learn More

Light microscopy is a well-established tool to study protein dynamics and protein functions in fixed and living cells. One limitation of light microscopy is that its diffraction limit (optical resolut...
Learn More

UW-Madison researchers have developed a novel mass spectrometry (MS)-based method for simultaneous qualitative and quantitative protein citrullination analysis from biological and clinical samples. Th...
Learn More

Coherent light sources, in which the photons have highly matched frequencies and phases, are commonly produced by lasers. In a laser, the atoms of a laser medium are stimulated to excite the electrons...
Learn More

UW-Madison and Morgridge Institute researchers have identified developed an improved method for depositing samples on electron microscopy (EM) grids. The technology leverages a modified mass spectrome...
Learn More

UW-Madison researchers have developed cell-based DNA sensors to achieve easy, accurate, and cost-effective detection of pathogens. Using synthetic biology, the inventors engineered the naturally compe...
Learn More

A UW-Madison researcher has developed an improved method and associated system for coherent multidimensional spectroscopy (CMDS). CMDS is based on the formation of Schrӧdinger cat states by exciting ...
Learn More

Building off of their prior discovery (Photo-Cleavable Surfactants P180335US02), UW-Madison researchers disclose an improved method for exosome proteomics. The method leverages the researchers’ phot...
Learn More

Soft materials are everywhere. In many applications, valuable information about the strength of these materials enables more precise control in everything from cutting and processing soft foods to des...
Learn More

Building off their earlier work with LC-infused multilayer films, the inventors developed a method for directly infusing LCs into porous PTFE membranes.  The resulting materials have desirable charac...
Learn More

UW-Madison researchers have developed a well-plate for cell culture that allows the user to finely define the location and temporal profile of multiple gradients including oxygen, nutrients, chemoattr...
Learn More

UW-Madison researchers have developed improved methods and systems for characterizing soil using visible-near-infrared spectroscopy (vis-NIRS) data. Combining their spectrographic data with additional...
Learn More

UW-Madison researchers and collaborators from Wesleyan University have shown, using an exceptional point (EP)-based PT-symmetric electromechanical accelerometer, that increases in technical noise can ...
Learn More

UW researchers have invented a Cesium Lattice Optical Clock (CLOC) for high performance and simple operation in a compact form factor. The novel design uses a “forbidden” optical transition in Cs ...
Learn More

A UW-Madison researcher has developed a method for predicting subsurface mechanical properties using distributed strain measurements obtained from applied perturbations. The method relies on model cha...
Learn More