Computed tomography (CT) systems are used for medical imaging and produce images by measuring the loss in an X-ray beam’s strength. These measurements are used to reconstruct an image in 2-D or 3-D...
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In recent years, statistical imaging reconstruction has been introduced in clinics by different computed tomography (CT) manufacturers as a means to reduce radiation dose levels. Essentially, the meth...
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Medical isotopes like molybdenum-99 are used for imaging patients and treating disease. Today, most radioisotopes are produced in nuclear reactors outside of the United States that employ highly enric...
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Intrinsic and extrinsic fluorescent markers can help surgeons target and rapidly identify tumorous tissue. The signals given off by these markers are relatively faint and normally viewed with a fluore...
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Although current microscopic optical systems are highly sensitive, they are generally bulky and expensive, and most have a severely limited field of vision. One alternative is adaptive microlenses tha...
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Assessing treatment response in cancer patients is essential to manage their disease and evaluate therapy. Computed tomography (CT) is widely used to monitor cancer treatment by measuring changes in t...
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The outcome of a stroke can hinge on the time spent on diagnosis and intervention. Perfusion imaging is a critical step in the process, wherein a patient is scanned to identify salvageable tissue. The...
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Medical isotopes are valuable healthcare tools for patient imaging and disease treatment. Yet most radioisotopes used in medicine are produced in nuclear reactors, which are complex, generate high vol...
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Compact solid-state LED/LD (light-emitting diode) light sources are by their nature near-point sources. Applications that take advantage of these highly efficient, spectrally engineered light sources ...
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Signal-to-noise ratio (SNR) is utilized in medical imaging as a quantitative measure of image quality. As SNR decreases, it becomes increasingly more difficult to differentiate between important anato...
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Of the various imaging techniques used to screen women for early-stage breast cancer, X-ray mammography has proven the most effective. Despite its success, however, this technique suffers from relativ...
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In a computed tomography (CT) system, an X-ray source projects a fan-shaped beam, which passes through the object being imaged and hits an array of radiation detectors. The source and detector array a...
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The HYPR method, as described in WARF reference number P06088US, reconstructs a composite image from acquired data to provide a priori knowledge of the subject being imaged. This composite image then ...
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In a computed tomography (CT) system, an X-ray source projects a fan-shaped beam, which passes through the object being imaged and hits an array of radiation detectors. The source and detector array a...
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In imaging technologies, signal-to-noise ratio (SNR) is a quantitative measure of image quality. In medical imaging specifically, as SNR decreases, it becomes increasingly difficult to differentiate b...
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Position emission tomography (PET) plays a vital role in the diagnosis of health and disease. The long-lived isotope iodine-124 (I-124; half-life 4.2 days) has many features that make it an attractive...
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X-ray mammography is currently the most effective method for detecting early-stage breast cancer; however, mammography suffers from relatively high false positive and false negative rates, requires pa...
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Microwave-based imaging methods, which exploit the contrast in dielectric properties between normal and malignant tissue, offer a promising alternative to ultrasound and X-ray techniques for imaging b...
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UW-Madison researchers previously developed a novel imaging technique for detecting breast cancer (see WARF reference number P01386US). This technique makes use of the sharp contrast in dielectric pro...
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Light-based diagnostics are used to create images of human tissue to detect the development of diseases like cancer. The popularity of light-based diagnostics is growing due to their non-intrusive nat...
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Measurements of emission and absorption spectra provide a valuable means of identifying and analyzing gases, liquids and solids. Fourier transform infrared (FTIR) and grating spectrometers are two com...
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Terahertz (THz) radiation holds tremendous potential for applications ranging from medical imaging technology to security and public safety. So far, the use of THz radiation beams has been limited by ...
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Systems based on terahertz (THz) radiation technology show promise for communication and imaging applications.  These systems can penetrate through many materials and are sensitive enough to resonate...
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Phsyicians often use microscopic visual inspection followed by biopsy to detect cancer; however, this method is limited in many ways. Optical techniques are a promising alternative that allows clinici...
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Biomedical imaging allows physicians to detect the onset of disease, injury and other disorders at an early stage, and to monitor their progression.
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