Search Results
324 Results for 'Research Tools'
PAGE 2 OF 13
Technology
MULTIPLEXED DILEU-BIOTIN-AZIDE (DBA) TAG ENABLED ISOBARIC TANDEM ORTHOGONAL PROTEOLYSIS ACTIVITY-BASED PROTEIN PROFILING (ISOBOP-ABPP) PLATFORM FOR HIGH-THROUGHPUT QUANTITATIVE PAN-PTM ANALYSIS
UW-Madison researchers have developed a set of novel isobaric chemical tags, DiLeu-Biotin-Azide (DBA), that could be useful in proteomics, particularly quantification of post translational modificatio...
Learn More
Learn More
Lingjun Li, Miyang Li, Min Ma | P220286US02
Technology
NOVEL CELL LINES SUPPORTIVE OF ROBUST LACTATE DEHYDROGENASE VIRUS (LDV) INFECTION
A UW-Madison researcher has created a cell line capable of growing LDV virus in vitro. The inventor explains that he made an educated guess as to what the receptor for this virus might (CD163) be and ...
Learn More
Learn More
Adam Bailey, Teressa Shaw, Cody Warren | P230385US01
Technology
NOVEL CELL LINES SUPPORTIVE OF ROBUST ARTERIVIRUS INFECTION
A UW-Madison researcher has developed FcRn-overexpressing cell lines that are susceptible to arterivirus infection. Through a genetic screen, the inventor discovered that the neonatal Fc receptor (FcR...
Learn More
Learn More
Adam Bailey, Teressa Shaw, Cody Warren | P230384US01
Technology
UNIVERSAL METHOD FOR PARASITE AND EUKARYOTIC ENDOSYMBIONT IDENTIFICATION
UW-Madison researchers have developed and validated a novel “parasitome” method to accurately characterize parasites in samples. Like published metabarcoding protocols, the new method consists of ...
Learn More
Learn More
Tony Goldberg, Leah Owens | P220194WO01
Technology
Methods for Bioprinting Functional Human Neural Tissues
Su-Chun Zhang, a world-renowned neuroscientist and pioneer in stem cell research, has developed a method for printing neural tissues that allows cells to form neural networks in vitro. The human brain...
Learn More
Learn More
Su-Chun Zhang, Yuanwei Yan | P220006US02
Technology
ENGINEERED TRYPTOPHAN DECARBOXYLASES AND USES THEREOF FOR SYNTHESIZING TRYPTAMINE ANALOGS
UW-Madison researchers have identified several tryptophan decarboxylase (TDC) mutations for improving enzymatic activity towards substituted tryptamines. Having identified these mutations, the researc...
Learn More
Learn More
Andrew Buller, Allwin McDonald | P220120US02
Technology
Characterization Via Homologizing Disparate Speech Terminology
Aspects of the present disclosure from UW Madison researchers are directed to methods and apparatuses involving characterization via homologizing disparate speech terminology. As may be implemented in...
Learn More
Learn More
Joao Ricardo Reboucas Dorea, Rafael Ferreira | P200128WO01
Technology
SITE-SELECTIVE DEUTERATION OF AMINO ACIDS THROUGH DUAL PROTEIN CATALYSIS
UW-Madison researchers have developed a protein-based method for selective deuteration of amino acids. The inventors’ method leverages the aminotransferase DsaD, a PLP-dependent enzyme, and a small ...
Learn More
Learn More
Andrew Buller, Tyler Doyon | P220181US02
Technology
METHODS OF DESIGNING PRODUCTION OF MICROBIAL COMMUNITIES, METHODS OF PRODUCING MICROBIAL COMMUNITIES, AND MICROBIAL COMMUNITIES PRODUCED THEREBY
UW-Madison researchers disclose an improved method for generating diverse microbiomes. The method leverages growth media composition and species inoculum ratios to control the makeup of the consortia,...
Learn More
Learn More
Ophelia Venturelli, Bryce Connors, Brian Pfleger | P220011WO01
Technology
High-Throughput Tool for Developing Enzyme-Mimicking Catalysts
Catalysts play countless roles in modern society including production of fertilizer, synthesis of plastics and other ubiquitous materials and development of pharmaceuticals. However, many catalysts re...
Learn More
Learn More
Jeffrey Martell, Edward Pimentel, Justice Merrifield | P220207US02
Technology
MONOCLONAL ANTIBODY REAGENTS DIAGNOSTIC FOR CDHR3, THE RHINOVIRUS-C CELLULAR RECEPTOR PROTEIN, DOMAINS EC1, EC2, EC5 AND EC6
UW-Madison researchers have developed and characterized nine murine monoclonal antibody (mAb) reagents that react uniquely with the EC1 (2x), EC2 (2x), EC5 (3x), and EC6 (2x) extracellular cadherin re...
Learn More
Learn More
Ann Palmenberg, Marchel Hill, Kelly Watters, Xander Kessler | P230117US01
Technology
VACO6
A UW-Madison researcher has established a cell line, called VACO6, from a discarded tissue specimen of a surgically resected primary human colon cancer. The detailed characteristics of the clinical do...
Learn More
Learn More
James Willson | P230180US01
Technology
PROBIOTIC STRAIN COLLECTION TO STUDY PROPHAGES
UW-Madison researchers have developed a number of variants of lytic strain L. reuteri ∆Φ1attB1∆Φ2∆attB2 (WARF case P170020). They are:
L. reuteri∆Φ1, in which prophage #1 is deleted from th...
Learn More
Learn More
Jan Peter Van Pijkeren, Jeehwan Oh | P230139US01
Technology
PHOTO-CLEAVABLE SURFACTANTS
UW-Madison researchers have developed photo-cleavable anionic surfactants, particularly 4-hexylphenylazosulfonate (Azo) and sodium 4-hexylphenylazosulfonate derivatives, which can be rapidly degraded ...
Learn More
Learn More
Ying Ge, Song Jin, Tania Guardado Alvarez, Kyle Brown | P180335US03
Technology
Methods Of Genome Editing Including Controlled Opening Of Chromatin
UW-Madison researchers developed an improved method of gene editing human iPSCs through CRISPR-Cas. They added the histone deacetylase small molecule inhibitor Trichostatin A (TSA) before addition of ...
Learn More
Learn More
Krishanu Saha, Kaivalya Molugu | P220049US02
Technology
RHESUS MACAQUE INDUCED PLURIPOTENT STEM CELL (IPSC) LINE: LINE Rh2431
A UW-Madison researcher has developed a Rhesus Macaque induced pluripotent stem cell (iPSC) line, called the Rh2431 iPSC line.
Learn More
Learn More
John Maufort | P230112US01
Technology
UW-Madison researchers have developed a titin DNA construct (a ‘titin minigene plasmid’) that is useful for identifying agents that modulate the titin size reduction that correlates with age and l...
Learn More
Learn More
Wei Guo, Yanghai Zhang | P230097US01
Technology
CYNOMOLGUS MACAQUE INDUCED PLURIPOTENT STEM CELL (IPSC) LINE: LINE cy0657
A UW-Madison researcher has developed a Cynomolgus Macaque induced pluripotent stem cell (iPSC) line, called the cy0657 iPSC line.
Learn More
Learn More
John Maufort | P230113US01
Technology
METHOD FOR DIFFERENTIATION OF BRAIN MURAL CELLS FROM HUMAN PLURIPOTENT STEM CELLS
UW-Madison researchers disclose a new method for differentiating brain mural cells – encompassing pericytes and vascular smooth muscle cells – from hPSCs. The inventors used their previously discl...
Learn More
Learn More
Eric Shusta, Benjamin Gastfriend, Sean Palecek | P220005US02
Technology
Primatized Mouse
The present invention is a novel, primatized mouse model for studying the immune system of nonhuman primates in a relatively low-cost mouse. The UW-Madison inventor used a different source of immune c...
Learn More
Learn More
Matthew Brown | P210237US02
Technology
Organelle-Targeted Genetically-Encoded Voltage Indicators And Methods Of Use Thereof
UW researchers have developed modified genetically encoded plasma membrane voltage probes for monitoring mitochondrial and ER membrane voltage gradients. A fluorescence protein tag was coupled with a ...
Learn More
Learn More
Meyer Jackson, Masoud Sepehri Rad | P210400US02
Technology
ANTI-GATA2 MONOCLONAL ANTIBODIES
UW-Madison researchers have developed three novel monoclonal antibodies that all have exceptional activity against human and mouse GATA2.
Learn More
Learn More
Emery Bresnick, Daniel Matson | P220242US01
Technology
GENERATION OF RABBIT POLYCLONAL ANTIBODY FOR PKM2
A UW-Madison researcher has developed a rabbit polyclonal antibody for methylated PKM2. There are three PKM2 arginine methylation sites R445, R447, R455. The antibody was generated using peptides enco...
Learn More
Learn More
Wei Xu | P220296US01
Technology
GENETIC TOOLS FOR THE ENGINEERING OF BACTEROIDES
UW-Madison researchers have developed a CRISPR-based genome editing tool to study and modify PULs in B. uniformis. The B. uniformis PULs show distinct glycan-degrading functions and transcriptional co...
Learn More
Learn More
Ophelia Venturelli, Jun Feng | P220212US01
Technology
RBM20 ANTIBODY
A UW-Madison researcher has developed and characterized an anti-RBM20 polyclonal antibody rabbit preparation (which he calls the “RBM20 antibody”). The inventor expressed and purified the full len...
Learn More
Learn More
Wei Guo, Marion Greaser | P220238US01