40 Results for 'hector deluca'
PAGE 2 OF 2
Technology
2-methylene-19-nor-(23s)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone And 2-methylene-19-nor-(2
The invention provides 2-methylene-19-nor-(23R)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone (“GC-3”), 2-methylene-19-nor-(23S)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone (“HLV”), and re...
Learn More
Learn More
Hector DeLuca, Margaret Clagett-Dame, Lori Plum, Pawel Grzywacz, Grazia Chiellini | P05291US
Technology
2-methylene-1alpha-hydroxy-18,19,21-trinorvitamin D3 Analogs And Uses Thereof
This invention relates to vitamin D compounds, and more particularly to 2-methylene-1α-hydroxy-18,19,21-trinorvitamin D3 (SX-99) and to pharmaceutical formulations that include this compound. The inv...
Learn More
Learn More
Hector DeLuca, Rafal Barycki, Lori Plum, Margaret Clagett-Dame | P06328US
Technology
2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin D3 And Uses Thereof
This invention relates to vitamin D compounds, and more particularly to 2-methylene-1 α,25-dihydroxy-18,19,21-trinorvitamin D3 (DJ-55) and to pharmaceutical formulations that include this compound. T...
Learn More
Learn More
Hector DeLuca, Rafal Barycki, Lori Plum, Margaret Clagett-Dame | P06327US
Technology
2-methylene-(20s,25r)-19,26-dinor-vitamin D Analogs
This invention discloses 2-methylene-(20S,25R)-19,26-dinor-vitamin D analogs, and specifically 2-methylene-(20S,25R)-19,26-dinor-1α,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This comp...
Learn More
Learn More
Hector DeLuca, Lori Plum, Margaret Clagett-Dame, Grazia Chiellini, Pawel Grzywacz | P08090US
Technology
Once-A-Week Administration Of 25-Hydroxy Vitamin D3 To Sustain Elevated Steady-State Pharmacokinetic Blood Concentration
An oral dosage form comprising a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and ...
Learn More
Learn More
Hector DeLuca, Lori Plum, Margaret Clagett-Dame | P08138US02
Technology
2-methylene-19-nor Vitamin D2 Compounds
2-Methylene-19-nor-24(S) and 24(R) derivatives of 1α,25-dihydroxyvitamin D2 are disclosed. These compounds are characterized by minimal bone calcium mobilization activity and relatively high intestin...
Learn More
Learn More
Hector DeLuca, Sumithra Gowlugari, Rafal Sicinski | P02026US
Technology
Vitamin D Analog “DA2HE” to Treat and Prevent Polyps, Hyperplastic Intestinal Disorders
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Margaret Clagett-Dame, Lori Plum, Agnieszka Glebocka | P120347US02
Technology
Crystallized Vitamin D Analogs “MET-1” and “MET-2”
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Agnieszka Flores, James Thoden, Hazel Holden | P120098US02
Technology
2-Methylene-19-Nor-1Alpha-Hydroxy-17-Ene-Homopregnacalciferol
Vitamin D is a highly potent regulator of calcium homeostasis and plays an established role in cellular differentiation. A recently discovered class of vitamin D analogs, the 19-nor-vitamin D compound...
Learn More
Learn More
Hector DeLuca, Lori Plum, Bulli Padmaja Tadi, Margaret Clagett-Dame | P05148US
Technology
2-Methylene-18,19-Dinor-1Alpha-Hydroxy-Homopregnacalciferol
Vitamin D is a highly potent regulator of calcium homeostasis and plays an established role in cellular differentiation. A recently discovered class of vitamin D analogs, the 19-nor-vitamin D compound...
Learn More
Learn More
Hector DeLuca, Lori Plum, Rafal Barycki, Margaret Clagett-Dame | P05147US
Technology
Procedure For Crystallization Of (22e)-(24r)-2-Methylene-22-Dehydro-1alpha,24,25-Trihydroxy-19-Nor-Vitamin D3
Disclosed are methods of purifying the compound (22E)-(24R)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 to obtain the compound in crystalline form. The methods typically include the ...
Learn More
Learn More
Hector DeLuca, Margaret Clagett-Dame, Lori Plum, Agnieszka Flores, James Thoden, Hazel Holden | P180077US02
Technology
Vitamin D Analogs “3D-QM” and “3D-QMS” for Treating Cancer and Bone Diseases
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Lori Plum, Rafal Sicinski, Izabela Sibilska-Kaminski | P120087US02
Technology
Vitamin D Analogs “2EG” and “T-2EG-S” for Treating Cancer and Bone Disease
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Lori Plum, Rafal Sicinski, Izabela Sibilska-Kaminski | P120086US02
Technology
Vitamin D Analogs “1D-QM” and “1D-QMS” for Cancer, Bone Disease Therapy
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Lori Plum, Rafal Sicinski, Izabela Sibilska-Kaminski | P120085US02
Technology
Vitamin D Analogs for Treating Bone Cancers and Diseases
The hormonally active form of vitamin D, known as calcitriol or 1,25 dihydroxyvitamin D3, has shown promise for treating diseases ranging from osteoporosis to cancer to psoriasis. However, the hormone...
Learn More
Learn More
Hector DeLuca, Margaret Clagett-Dame, Lori Plum, Izabela Sibilska-Kaminski, Rafal Sicinski | P100358US03