Transfection is the process of introducing nucleic acids into cells. Two main strategies are viral (utilizing viruses as vectors) and non-viral. Non-viral methods are less efficient but attractive for...
Learn More

How and why precursor cells differentiate into tissue-specific cell types involves a complex interplay of signals and remains a rich topic of investigation. Outside of the body, for example, certain s...
Learn More

Mesenchymal stem cells (MSCs) are precursors to mesenchymal tissues, such as bone, dental tissue, cartilage, tendon, bone marrow stroma, hematopoietic lineages, and muscle. Bone marrow is a useful sou...
Learn More

Current methods for isolating and culturing primary (stem/progenitor) cells remain unsatisfactory because most primary cells die when transferred to culture, and the remaining cells usually develop mu...
Learn More

Dendritic cells are used as a base for vaccines and in the study of antigen processing within the human body. However, obtaining large quantities of the cells, which are generated in bone marrow, is l...
Learn More

Type I diabetes, one of the most common autoimmune diseases in humans, is caused by destruction of pancreatic islet beta cells. Although its symptoms can be controlled, the disease is irreversible. Tr...
Learn More

Human embryonic stem (hES) cells have the potential to provide a source of specific cell types for research and ultimately, for therapeutic transplantation into humans.
Learn More

Human embryonic stem (hES) cells are capable of self-renewal, as long as they remain undifferentiated. Culture conditions, including the medium and substrate the cells are grown in, play an important ...
Learn More

Under physiological conditions, bone tissue regeneration involves a complex interplay of multiple biologically active molecules and stem cells. The molecules are often presented sequentially in cascad...
Learn More

The normal growth and development of tissue requires a complex interplay of multiple signals from multiple genes in well-defined locations, leading to the controlled differentiation of precursor cells...
Learn More

Human embryonic stem (ES) cells are potentially capable of supplying cells and tissues for replacement of defective human tissue. However, procedures currently used to culture human ES cells involve t...
Learn More