Artificial bone implants require a unique combination of properties. They must be non-toxic, resistant to corrosion, easily machined, biocompatible, and have low density. With these properties in mind...
Learn More

UW-Madison researchers have discovered a new polymer blend based on polyisobutylene (PIB) that can simultaneously achieve a very low water permittivity under dynamic straining conditions, while also r...
Learn More

A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of spaced apart walls comprising a biodegradabl...
Learn More

Disclosed herein are methods for modifying a substrate having a hydrophobic surface. Also disclosed are modified hydrophobic substrates. The modified hydrophobic substrates and methods disclosed herei...
Learn More

Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50. Current c...
Learn More

"Orthobiologics" provides an improved method of treating fractures and other bone defects. This therapy employs inductive molecules, such as bone morphogenetic protein-2 or bone morphogeneti...
Learn More

The ability to control the delivery of biomolecules to cells and tissues has many therapeutic and research applications. In particular, spatial and temporal control over the release of multiple biolog...
Learn More

Transfection is the process of introducing nucleic acids into cells. Two main strategies are viral (utilizing viruses as vectors) and non-viral. Non-viral methods are less efficient but attractive for...
Learn More

Methods that allow reactive polymer films to be deposited or assembled on topologically complex substrates are useful for the patterning or chemical modification of surfaces in a broad range of applic...
Learn More

The ability to deliver proteins into cells has many therapeutic and research applications. However, peptide drugs and therapeutic proteins are notoriously difficult to administer, in part because of t...
Learn More

A fracture requiring orthopedic treatment occurs approximately every 14 seconds in the United States.  Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bo...
Learn More

Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50.  Bone-te...
Learn More

Thin films and coatings that allow the sustained release of DNA from surfaces play an important role in the development of localized approaches to gene therapy. For example, polymer-coated intravascul...
Learn More