UW-Madison researchers have developed a novel camelid antibody against the cancer target cMET. As cMET is overexpressed on many tumors, this antibody may be useful for imaging tumors and/or delivering...
Learn More

UW-Madison researchers have developed monoclonal antibodies to ketamine and monoclonal antibodies to 6-HNK, one of the major metabolites of ketamine. The antibodies are selective enough to bind to the...
Learn More

UW-Madison researchers have developed a method of diagnosing cancer through detection of specific fragmentation patterns of cell free DNA in plasma. Their approach is distinctly focused on positioning...
Learn More

UW-Madison researchers have discovered that the midbody (MB) functions as an RNA-based organelle with active translation activity, which serves as a novel means of RNA-based intercellular communicatio...
Learn More

A UW researcher has developed a higher throughput method for detection of the methylation pattern of the alleles involved in Prader-Willi and Angelman disorders from dried blood spots. This method pro...
Learn More

A UW-Madison researcher has developed a new diagnostic assay for Sjogren's syndrome, based on her discovery of novel autoantibodies relevant to the disease process. Using whole peptidome array tec...
Learn More

UW-Madison researchers have developed a genetic rescue assay that discriminates the activities of wild type DDX41 from those of human myeloid malignancy-associated germline and somatic DDX41 mutants. ...
Learn More

Metagenomics is the study of genetic material from environmental samples for detecting microbes, especially pathogens. It is increasingly used within clinical and industrial settings. While metagenomi...
Learn More

UW-Madison researchers have developed and validated a novel “parasitome” method to accurately characterize parasites in samples. Like published metabarcoding protocols, the new method consists of ...
Learn More

Detection of genetic aberrations using nucleic acids as biomarkers can be a powerful strategy for disease diagnosis and progression monitoring; however, the high heterogeneity of cells within a patien...
Learn More

UW-Madison researchers have developed mass spectrometry (MS) compatible nanoparticles for the selective capture and enrichment of low abundance proteins. The surface of superparamagnetic nanoparticles...
Learn More

UW-Madison researchers have developed three novel monoclonal antibodies that all have exceptional activity against human and mouse GATA2.   
Learn More

UW – Madison researchers have determined that SARS-CoV-2 infection induces antibodies against both structural and non-structural proteins and they identified epitopes in the SARS-CoV-2 membrane prot...
Learn More

The current gold standard method for COVID-19 testing is a multi-step protocol 25 involving RNA extraction using column-based or magnetic bead-based methods, followed by RT-qPCR-based detection of the...
Learn More

Systems for monitoring metabolites may include a sample collection system and a urinalysis system of or for a toilet.  The sample collection system may be automated to collect sample urine from a toi...
Learn More

Differentially methylated positions associated with hypersomnolence, idiopathic hypersomnia, and long sleep time are provided herein along with biomarker panels thereof and methods of diagnosing and p...
Learn More

The present disclosure provides for methods of diagnosing and treating bacterial infections. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to glycan components on bacteria including ...
Learn More

The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for selecting candidate vaccine recipients, ...
Learn More

Devices and methods for using changes in the configuration of micrometer sized dispersed liquid crystal domains to detect or quantify analytes in a test sample, including endotoxin lipopolysaccharide ...
Learn More

Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed.
Learn More

It is estimated that half of new HIV infections in the U.S. are from patients who know they are HIV-positive but underestimate their transmissibility. Identifying and monitoring the latent HIV reservo...
Learn More

Gram-negative bacterial infections are an ongoing challenge to health care providers worldwide. Detection, treatment and control of such pathogens have gained increasing importance in the context of a...
Learn More

Mycobacterial infections cause major health problems for people and animals, including human tuberculosis, bovine tuberculosis and Johne’s disease. Johne’s disease (or paratuberculosis) afflicts 9...
Learn More

Fungal infections such as aspergillosis and Valley Fever can be life threatening, particularly in immune-compromised patients. These patients are vulnerable to fungal strains that flourish in hospital...
Learn More

Blastomyces dermatitidis is a soil fungus found throughout the world, and is especially prevalent in the river valleys and Great Lakes region of the United States. If spores are inhaled, blastomycosis...
Learn More