A UW-Madison researcher has developed a technique for mechanical manipulation of biological tissues. Short ultrasound pulses or bursts, delivered at intermediate intensity to the target tissue transmi...
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Materials engineering for synthetic vascular grafts to repair damaged or diseased blood vessels is driven by biomimetic innovations that improve biocompatibility and flexibility. A significant challen...
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A UW-Madison clinician has developed a bean-shaped roller with an integrated heating element for treatment of meibomian gland dysfunction (MGD). The roller rotates towards the lash line to massage the...
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UW-Madison researchers have developed a "localizable" liver gene therapy system that substantially reduces the escape of the gene vectors from the tissue mass or organ, e.g., the liver, such...
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UW-Madison researchers have developed a digitally controlled CSF drainage device for use in the ICU setting that provides improved precision and safety. The novel design significantly reduces over or ...
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UW-Madison researchers have developed a new stent design that uses piezoelectric biomaterials to generate a localized, low-intensity electric field driven by blood pressure fluctuations. The self-gene...
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UW-Madison researchers have developed a presurgical skin treatment device that uses blue light (415 nm) coupled with a real-time, skin-positioned dose sensor to eradicate C. acnes while reducing skin ...
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A UW Madison physician and local dentist have designed a specialized bite block device for use with endotracheal tubes. The device protects the front teeth by using the molars on both sides of the ja...
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UW-Madison researchers have developed a nanocrystals capable of delivering biologic payloads. Exemplary payloads include nucleic acids, proteins, and peptides, all of which have shown promise as vacci...
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Two UW-Madison researchers have developed a sequential coating strategy to improve the efficacy of probiotics used in the treatment of IBD.  The probiotic is first coated with a tannic acid (TA) laye...
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The inventors have developed methods for creating tannin-chitosan composite thin-films incorporating active pharmaceutical ingredients, including psilocybin (a psychedelic) and biosimilars (melatonin ...
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An active microneedle array and method are provided for penetrating an outer layer of an epidermis. The active microneedle array includes a base having first and second sides. The first side of the ba...
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Axial stress or similar properties in a stressed connective tissue may be assessed during surgery by excitation of the ligament to create a shear wave allowing measurement of the shear wave velocity w...
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Various aspects of the present disclosure characterize apparatuses and/or methods as may be implemented with a variety of prosthetic components and applications. As may be consistent with one or more ...
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A bone stent facilitates bone fixation via interior contact, as may be useful for flexible entry into a sidewall of an elongated bone. As consistent with one or more embodiments, a stent includes prox...
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Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-...
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An office chair that is ergonomically configured to allow for the coordination of stretches to the pectoralis minor muscle, trapezius muscle, and scalene muscles to open up the thoracic outlet, releas...
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Described herein are hybrid nanoparticles that are exosomes loaded with one or more nanoparticle dendrimers. Also included are pharmaceutical compositions including the hybrid nanoparticles and method...
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A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape o...
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Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonuclei...
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Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral l...
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Disclosed are formulations for providing an active agent. Formulations include a carrier including an active agent and mineral coated microparticles wherein an active agent is adsorbed to the mineral....
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A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The elect...
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Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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Growth factor regulation is a key function of the extracellular matrix and critical for proper blood vessel growth and maturation during wound healing. In particular, blood vessel sprouting is essenti...
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