The invention provides biheteroaryl dicarboxylates and esters, and salts thereof which are useful generally as modulators of CP4H activity, more particularly as inhibitors of CP4H, or further as chemi...
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Described herein is a mono-end PEGyated functional upstream domain (FUD), pharmaceutical compositions, and its use to inhibit fibrosis such as organ fibrosis, idiopathic pulmonary fibrosis and fibrosi...
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Novel synthetic human scale collagen triple helices assemblies are disclosed. Methods of making self-assembling collagen mimetic peptides that self-assemble into human scale collagen are also disclose...
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Voice impairment (dysphonia) affects an estimated 20 million people in the U.S., resulting in reduced quality of life and direct health care costs exceeding $11 billion per year. Between 60 and 80 per...
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Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing.Given its signifi...
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The global cosmetics industry is a $460 billion dollar market with the skin whitening sector valued at $381 million in 2014. This growing market is projected to increase at a CAGR of 11.7%, reaching $...
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Wound healing is a complex and dynamic process of rebuilding skin and tissue. Chronic or impaired wounds result when tissues fail to progress through the necessary stages of healing. This is a signifi...
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Collagen, the most abundant protein in vertebrates, serves as the fundamental structural protein for vertebrate tissues. Collagen is a fibrous protein consisting of three polypeptide chains that fold ...
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Collagen, the most abundant protein in vertebrates, provides structure for tissues and plays a key role in wound healing. In connective tissue, individual collagen molecules are wound together in tigh...
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Collagen is the most abundant protein in vertebrates. It serves as the fundamental structural protein for vertebrate tissues and is critically important in wound healing. Many diseases, including arth...
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