Therapeutics & Vaccines
Vectors For Eliciting Immune Responses To Non-Dominant Epitopes In The Hemagglutinin (Ha) Protein
WARF: P190028US02
Inventors: Yoshihiro Kawaoka, Gabriele Neumann, Huihui Kong
The Invention
Methods of preparing influenza viruses having altered immunodominant epitopes in HA, e.g., having one or more residues in one or more of antigenic sites A-E in HA altered, and viral vectors, e.g., influenza virus VLPs or non-influenza viruses or VLPs thereof expressing or having influenza HAs with altered immunogenicity as a result of altered immunodominant epitopes therein are provided.
Tech Fields
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854