Therapeutics & Vaccines
MODULAR DENDRON MICELLES FOR COMBINATION IMMUNOTHERAPY
WARF: P210003WO01
Inventors: Seungpyo Hong, Deric Wheeler
The Invention
UW-Madison researchers have developed a nanoparticle-based platform comprising targeting agents (i.e., tumor selective peptides) and active agents (e.g., immuno- and chemo-drugs). The nanoparticles comprise hyperbranched dendrons, linear hydrophobic polymers, and a polyethylene glycol (PEG) corona. When functionalized, these materials self-assemble into immunotherapeutic dendron-micelles, which can be administered as a pharmaceutical formulation. Given their adaptability, the dendrimer-micelle nanoparticles could be further functionalized to existing radiation therapy agents, further enhancing their functionality.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847