Therapeutics & Vaccines
CRYPTIC PROTEINS EXPRESSED FROM DEFECTIVE VIRAL GENOMES INTERFERE WITH INFLUENZA VIRUS REPLICATION
WARF: P230056US02
Inventors: Andrew Mehle, Jordan Ranum, Mitchell Ledwith
The Invention
UW-Madison researchers have developed methods for making and using modified influenza gene products, alone or in combination, to inhibit WT virus replication, to serve as immunostimulatory agents, or as attenuated vaccine backbones. This discovery allows for fine-tuning and optimization of the inhibitory activity of DIPs, producing a dual effect in which both the RNA itself and the novel protein it encodes coordinate to interfere with replication.
Additional Information
For More Information About the Inventors
Tech Fields
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854