Therapeutics & Vaccines
IMPROVED INFLUENZA VIRUS REPLICATION FOR VACCINE DEVELOPMENT
WARF: P230109US02
Inventors: Yoshihiro Kawaoka, Gabriele Neumann, Lizheng Guan
The Invention
UW-Madison researchers have identified new mutations that promote replication of influenza A viruses to high titers in embryonated chicken eggs and would therefore increase the manufacturing yield for influenza vaccine viruses. Those replication-enhancing mutations are PB2 Q439H, PB1 K577R, PB1 M640V, M1 K35R, PB1 G62E, and PB1 L624I.
Tech Fields
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854