Therapeutics & Vaccines

Single-Domain Antibodies and Variants Thereof Against Opioids
WARF: P230209US02
Inventors: Aaron LeBeau, Joseph Gallant, Marco Pravetoni, Carly Baehr, Hideki Aihara, Dustin Hicks
The Invention
UW-Madison researchers and collaborators have developed a suite of four camelid antibodies that specifically bind to fentanyl and carfentanil, a major metabolite of fentanyl. One binds specifically to fentanyl, one binds specifically to carfentanil and two are cross-reactive.
The inventors have a crystal structure of the antibody specific to fentanyl, JGFN4. They plan to do additional work on this antibody with a collaboration at the University of Washington.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847