This 60-minute discussion – the second in our Shaping the Endless Frontier series – includes congressional co-sponsors and advocates of the Endless Frontier Act who explain why now is the time, and the Midwest is the place, for bold investments in science, technology and innovation. For the last century, the United States had been the undisputed, global leader in university and industry research. Our panelists discuss how targeted federal investment in emerging growth centers focused on quantum computing, artificial intelligence, biotechnology and manufacturing can extend and expand U.S. leadership into the twenty-first century and beyond.