An interface unit for epicardial pacemaking and telemetry monitoring connects a pacemaker and bedside monitor for simultaneous pacing during electrogram visualization using epicardial pacing leads. Th...
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Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonuclei...
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A disposable speculum for an otoscope provides an attached forward-facing pressure sensitive adhesive for adhering to and extracting foreign bodies from the ear canal. Attaching the pressure sensitiv...
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The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral l...
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Disclosed are formulations for providing an active agent. Formulations include a carrier including an active agent and mineral coated microparticles wherein an active agent is adsorbed to the mineral....
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A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The elect...
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Disclosed herein are methods for modifying a substrate having a hydrophobic surface. Also disclosed are modified hydrophobic substrates. The modified hydrophobic substrates and methods disclosed herei...
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Disclosed herein are novel wavy, multi-component vascular grafts (WMVGs) with a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers and a method for preparing W...
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A disposable speculum for an otoscope provides a sheath adapted to cover an elongate otoscope probe and providing inwardly extending tabs that are adapted to flex outward when the speculum is inserted...
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Aspects of the disclosure are directed to methods and/or apparatuses involving the deployment and coupling of catheters. As may be implemented in accordance with one or more embodiments, each of first...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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A comfortable device for treating sleep apnea incorporates a mask, a flexible hose and a chamber for collecting expired air containing CO2. A sensor detects apnea and a control system automatically ad...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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A method and device are provided for detecting a target in a biological sample. The target binds to a solid phase substrate. First and second cavities in a plate are filled with an oil. The first and ...
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The importance of face shields in preventing the transmission of infectious agents is increasingly well established. Typically, a face shield will include a headband that can be clamped about the head...
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In 2016, approximately 135,000 new cases of colon and rectal cancers will be diagnosed and nearly 50,000 will die from this disease, making it the one of the most common causes of cancer related death...
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A new cancer treatment being studied at a few major centers including UW Health is CAR T (Chimeric Antigen Receptor T cell) therapy. CAR T therapy uses a patient's own cells and 'reengineers&#...
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The importance of T cells in immunotherapy is driving the development of technologies to better characterize T cells and improve therapeutic efficacy. One specific objective is assessing antigen-induc...
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The separation or isolation of proteins from a heterogeneous mixture is a common practice in scientific experimentation and the manufacturing of biologic reagents. Commercially available kits and cur...
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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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Bacterial contamination is a major risk in biologics manufacturing and the presence of endotoxin, an outer membrane component of Gram-negative bacteria, is vigorously tested for in protein and DNA/RNA...
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Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50. Current c...
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