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179 Results for 'Medical Devices'
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Technology
‘Smart’ Cerebrospinal Fluid Shunt
Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Bermans Iskandar, Joshua Medow, Christopher Luzzio, John Webster, Mehdi Shokoueinejad Maragheh, Fa Wang, Xuan Zhang | P170214US01
Technology
Slippery Liquid-Infused Porous Surfaces (SLIPS) with Improved Antifouling Properties, Small Molecule Release
Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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David Lynn, Uttam Manna | P160308US02
Technology
Liquid Crystal-Based Assay for Rapid and Precise Detection of Endotoxin in the Presence of Masking Agents
Bacterial contamination is a major risk in biologics manufacturing and the presence of endotoxin, an outer membrane component of Gram-negative bacteria, is vigorously tested for in protein and DNA/RNA...
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Nicholas Abbott, Christopher Murphy, Jugal Gupta, I-Hsin Lin | P09241US02
Technology
Modular Peptide Binds to Biomaterials and Promotes New Bone Formation
Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50. Current c...
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William Murphy, Jae Sung Lee, Mark Markel, Ben Graf | P09202US
Technology
Minimally Invasive Microwave Ablation Antennas
Microwave ablation is a minimally invasive method for treating cancer, especially solid tumors. The method uses an interstitial antenna that heats tissue with microwave energy.These antennas require c...
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Nader Behdad, Susan Hagness, Hung Luyen | P140132US01
Technology
A Low-Cost, Dosimeter Accessory Kit Enabling the Collection of Accurate Sound Level Measurements from within the Ear Canal
Noise level in the workplace is a concern and is monitored by the Occupational Safety and Health Administration (OSHA). In many instances, providing some form of hearing protection is an easy solution...
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Lynn Gilbertson, Donna Vosburgh, Tim Klein | T150024US02
Technology
Noninvasive Assay for Bovine Embryo Quality
Selection intensity for higher milk production in dairy cattle has contributed to a decline in fertility, posing a challenge to dairy producers. Despite technological advances, the pregnancy rate of c...
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Hasan Khatib, Jenna Kropp | P150131US02
Technology
Predicting Glucoregulatory Dysfunction
The term glucoregulatory dysfunction covers a spectrum of disorders from insulin resistance to prediabetes and diabetes. Problems associated with glucoregulatory dysfunction and obesity dominate healt...
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Dhanansayan Shanmuganayagam, Rozalyn Anderson, Ricki Colman, James Ntambi, Mary Lindstrom, Michael Polewski, Maggie Burhans | P150057US02
Technology
Growth Factor Regulation in Blood Products for Improved Wound Healing
Growth factor regulation is a key function of the extracellular matrix and critical for proper blood vessel growth and maturation during wound healing. In particular, blood vessel sprouting is essenti...
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William Murphy, David Belair, Ngoc Nhi T. Le, Michael Toepke, Nicholas Impellitteri, Connie Chamberlain | P160179US01
Technology
More Stable Collagen Mimetic Peptides for Wound Healing
Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing.Given its signifi...
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Ronald Raines, Ismet Tanrikulu | P140407US02
Technology
Implantable Cancer Drug Delivery Device Signals the Future of Personalized Medicine
Cancer treatment planning remains an ongoing challenge to oncologists and patients alike, with each cancer being genetically unique and requiring personalized approaches. Greater outcome success will ...
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David Beebe, Mark Burkard, Jay Warrick, David Guckenberger, Lee Wilke | P150255US01
Technology
Improved System for Stroke Therapy and Rehabilitation
Each year approximately 780,000 Americans experience a new or recurrent stroke. Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of long...
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Justin Williams, Vivek Prabhakaran | P09245US02
Technology
Identification of Disease Characteristics Using Isotope Ratios in Breath
UW-Madison researchers previously described a method of determining whether or not an animal is suffering from a catabolic change by sampling isotope changes in breath or blood.
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Warren Porter, Mark Cook, Fariba Assadi-Porter, Daniel Butz | P05416US
Technology
Detection of the Catabolic State by Determining the Rate of Systemic Oscillations in Carbon Isotope Ratios
The catabolic state refers to the condition where the body uses stores of carbohydrates, amino acids or fats as a source of energy for maintenance. The catabolic state may be induced by infection, dis...
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Hamid Eghbalnia, Mark Cook, Warren Porter, Daniel Butz | P09010US
Technology
Otoscope Providing Improved Ear Canal Access
An otoscope is a classic, handheld medical device that allows a doctor to look into the ear canal and tympanic membrane (eardrum). This is important for diagnosing ear infections, membrane ruptures an...
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James Berbee, Azita Hamedani, Gregory Rebella | P140406US01
Technology
Minimally Invasive Spinal Fusion
An estimated eight out of 10 people will be affected by a spine condition during their lifetime, making treatment options like spinal fusion surgery imperative. Spinal fusion is a surgical procedure i...
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Nathaniel Brooks, Meghan Anderson, Hannah Meyer, Hannah Pezzi, Amy Slawson, Andrea Schuster | P140303US01
Technology
Foot Harness for Patients Relearning to Walk
Walking impairment can be caused by many factors such as aging, traumatic brain injury, cerebral palsy and other conditions that disrupt balance and posture. Stroke, for example, is the leading cause...
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Kreg Gruben, Wendy Boehm | P150292US01
Technology
Improved Neuron Electrode Array Uses Graphene
During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Zhenqiang Ma, Justin Williams, Dong-Wook Park, Amelia Schendel, Solomon Mikael | P140254US01
Technology
Biomarkers for Detecting Prostate Cancer
Prostate cancer is the second most common cancer in American men, causing more than 27,000 deaths every year. An estimated one man in seven will be diagnosed with prostate cancer during his lifetime.E...
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David Jarrard, Bing Yang | P130258US03
Technology
Monitoring Tumor Ablation in Real Time
As an alternative to surgery, thermal ablation is a method of treating tumors of the liver, kidney, lung and other body parts. In the process, a slender antenna or probe is inserted through the skin t...
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Christopher Brace, Peng Wang | P130294US01
Technology
Surgical Manipulator with Finer Motion Control and Capability
Minimally invasive surgeries – including robotic procedures – utilize manipulators, which are inserted into patients to help maneuver tissue or tools. Manipulators can be classified either as rigi...
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Michael Zinn | P130344US01
Technology
An Orthopedic Implant Coating for Enhanced Bone Growth
"Orthobiologics" provides an improved method of treating fractures and other bone defects. This therapy employs inductive molecules, such as bone morphogenetic protein-2 or bone morphogeneti...
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William Murphy, Jae Sam Lee, Mark Markel, Ben Graf | P07031US
Technology
Bedside Diagnosis of Swallowing Disorders
Approximately 15 million Americans suffer from a swallowing disorder (dysphagia). People with acid reflux, a neurological disorder or cancer of the head and neck are particularly at risk. The leading ...
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Matthew Hoffman, Jack Jiang, Timothy McCulloch, Zhixian Geng | P130237US01
Technology
Multilayered Films for the Controlled Release of Anionic Molecules, Including Nucleic Acids
The ability to control the delivery of biomolecules to cells and tissues has many therapeutic and research applications. In particular, spatial and temporal control over the release of multiple biolog...
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David Lynn, Jingtao Zhang, Xianghui Liu | P08128US02
Technology
Eardrum Nanomembrane Offers Tinnitus Care
Tinnitus is the perception of a sound with no external source. The sounds could be produced within a patient’s own body, like crackling caused by muscle spasms, or wholly imagined. Either way, diagn...
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Robert Blick, Burke Richmond | P120327US01