Although current microscopic optical systems are highly sensitive, they are generally bulky and expensive, and most have a severely limited field of vision. One alternative is adaptive microlenses tha...
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Magnetic resonance (MR) imaging technology is used to measure nuclear magnetic resonance (NMR) from various substances in human tissue to produce medical images for qualitative and quantitative assess...
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With the advance of photon counting technology, spectral CT (multi-energy CT) has attracted lots of attention. The technique utilizes X-ray spectral information to identify and differentiate materials...
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The problem of constructing a set of points uniformly distributed across the surface of a sphere dates to the early 20th century. The problem is of great importance to modern biomedical imaging and ma...
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Elastography is a medical procedure analogous to conventional palpation.  It is commonly used to detect tumors and other abnormalities that cause changes in local tissue stiffness.  Quasi-static ela...
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Since the introduction of angiography, there have been many attempts to develop techniques that provide diagnostic images of the vasculature while reducing invasiveness.A technique called 4-D DSA (dig...
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Iterative image reconstruction techniques can be used to produce high quality tomographic images from noise-contaminated data. It is known that a statistical weight is critical for great image quality...
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In magnetic resonance imaging (MRI), the amount of data required to reconstruct an image can be decreased using ‘partial k-space’ sampling. This type of sampling enables shorter breath-holds, redu...
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With conventional image reconstruction, a single image is produced from a corresponding set of data. For example, an image can be reconstructed from a single CT sonogram or one MRI data set. Such dire...
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Assessing treatment response in cancer patients is essential to manage their disease and evaluate therapy. Computed tomography (CT) is widely used to monitor cancer treatment by measuring changes in t...
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Magnetic resonance spectroscopy (MRS) provides a noninvasive means of discovering and quantifying chemical compounds within an area of interest like the brain. The underlying principle is that the ato...
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Magnetic resonance parametric mapping is a general framework for measuring important biomarkers. In the process, several images from the same field of view are obtained using different acquisition par...
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Elastography is a type of imaging technique that reveals the stiffness of tissues. It commonly is used to detect tumors and other abnormalities that cause changes in local tissue stiffness. Measuremen...
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Preterm birth affects 13 million babies every year, resulting in infant deaths, disabilities and medical conditions costing $26 billion annually in the U.S. alone. Preterm birth rates have increased i...
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The outcome of a stroke can hinge on the time spent on diagnosis and intervention. Perfusion imaging is a critical step in the process, wherein a patient is scanned to identify salvageable tissue. The...
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Interventional medical procedures can be performed less invasively, and more safely, when guided by magnetic resonance imaging (MRI). Placing devices like catheters, guidewires and stents using MRI gu...
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Acquiring diagnostic images of a patient’s vasculature can be difficult and time consuming. Some magnetic resonance imaging (MRI) techniques employ contrast-enhancing agents, such as gadolinium, tha...
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Iron is an essential nutrient for the human body but is toxic in excess. Iron overload is a particular hazard to patients requiring regular blood transfusions. Treatment for patients with iron overloa...
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Medical isotopes are valuable healthcare tools for patient imaging and disease treatment. Yet most radioisotopes used in medicine are produced in nuclear reactors, which are complex, generate high vol...
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Visualizing a patient’s heart by non-invasive cardiovascular imaging is a powerful tool for diagnosis and therapy. Yet the heart’s movement and small branching arteries make quality cardiac imagin...
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MRI produces medically valuable images of a patient’s internals using magnetic fields and pulses that align and excite nuclei. The signals emitted by excited nuclei can be measured in ‘k-space’ ...
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Magnetic resonance imaging (MRI) of metallic implants can be challenging because metal and surrounding tissue impact the main magnetic field differently. Such magnetic field inhomogeneities cause off-...
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A leading method for reducing motion blurring in medical imaging is called PROPELLER (Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction). It allows doctors to track and help...
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Quantitative magnetic resonance imaging (qMRI) is a clinical procedure that can yield imaging biomarkers more sensitive and specific to underlying disease than regular MRI. It works by fitting images ...
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Compact solid-state LED/LD (light-emitting diode) light sources are by their nature near-point sources. Applications that take advantage of these highly efficient, spectrally engineered light sources ...
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