Wisconsin Alumni Research Foundation

Technology

Cell Line Stably Expressing KvLQT1 and minK

One of the key potassium channels in the heart is formed by the co-assembly of protein products from the KvLQT1 (KCNQ1) and minK (KCNE1) genes, which produce the slowly activating delayed rectifier po...
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Craig January, Sridharan Rajamani, Corey Anderson | P03073US

Technology

Membrane Cascade-Based Separation

Purification of biological components, including viruses, plasmids, proteins and small molecules, typically relies on chromatography for most of the separation steps. Membrane filtration cascades prov...
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Edwin Lightfoot | P04423US

Technology

Method to Screen for Novel Antibiotics

The antibiotic vancomycin targets the peptidoglycan-containing bacterial cell wall. Inducible resistance to vancomycin and other glycopeptide antibiotics is becoming a serious health problem, necessit...
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Bernard Weisblum, Robert Giannattasio, Arcady Grenader, Andrew Ulijasz, David Kovalic | P96061US

Technology

Cell-Permeable Green Fluorescent Protein

The green fluorescent protein (GFP) from the jellyfish Aequorea victoria is an extremely useful tool in biochemistry, molecular biology and diagnostics. This protein has been used to study gene expres...
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Ronald Raines, Stephen Fuchs | P06084US

Technology

Tsp1 -/- Stz Mice, A Model For Diabetes

Effective and non-destructive treatments are needed for diabetic retinopathy, a major cause of blindness in the United States. Thrombospondin1 (TSP1), a matricellular protein that inhibits angiogenesi...
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Nader Sheibani-Karkhaneh, Christine Sorenson | P06036US

WARF